<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-7203</journal-id>
<journal-title><![CDATA[Acta médica Grupo Ángeles]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. Grupo Ángeles]]></abbrev-journal-title>
<issn>1870-7203</issn>
<publisher>
<publisher-name><![CDATA[Grupo Ángeles, Servicios de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-72032018000300226</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Adherencia terapéutica: un problema de atención médica]]></article-title>
<article-title xml:lang="en"><![CDATA[Therapeutic adherence: a health care problem]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortega Cerda]]></surname>
<given-names><![CDATA[José Juan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Herrera]]></surname>
<given-names><![CDATA[Diana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez Miranda]]></surname>
<given-names><![CDATA[Óscar Adrián]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortega Legaspi]]></surname>
<given-names><![CDATA[Juan Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Grupo Ángeles Servicios de Salud  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Ángeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad La Salle  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,University of Washington Department of Medicine ]]></institution>
<addr-line><![CDATA[Seattle Washington]]></addr-line>
<country>USA</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2018</year>
</pub-date>
<volume>16</volume>
<numero>3</numero>
<fpage>226</fpage>
<lpage>232</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-72032018000300226&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-72032018000300226&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-72032018000300226&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Hoy en día, es ampliamente sabido que la falta de adherencia al tratamiento es la principal causa de que no se obtengan todos los beneficios que los medicamentos pueden proporcionar a los pacientes; sin embargo, en la práctica clínica diaria, seguimos sin reconocer este hecho como la primera causa de fracaso terapéutico, recurriendo con frecuencia a la intensificación de tratamientos o pruebas innecesarias que pueden poner en riesgo al paciente. La falta de adherencia terapéutica es un problema de gran impacto a nivel mundial, predominando sobre todo en pacientes con enfermedades crónicas, en las cuales la adherencia a largo plazo comprende poco más del 50%, pero es más baja en países en desarrollo. Como consecuencia, tenemos mayores tasas de hospitalización, aumento en los costos sanitarios y fracasos terapéuticos, entre otros problemas. Según la Organización Mundial de la Salud (OMS), existen cinco factores que intervienen en la adherencia terapéutica: 1: socioeconómico, 2: relacionados con el tratamiento, 3: relacionados con el paciente, 4: relacionados con la enfermedad y 5: relacionados con el equipo sanitario. A pesar de que se han descrito diversos planes para mejorar la adherencia, con la evidencia disponible hasta el momento no se puede recomendar una estrategia específica que sea eficaz y que sirva en todos los casos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: It is widely known that the lack of adherence to treatment is the main cause of not obtaining all the benefits that medicines can provide to patients, and yet, in daily clinical practice, we continue not to integrate this fact as the first cause of therapeutic failure, often resorting to the intensification of treatments or unnecessary tests that can put the patient at risk. The lack of therapeutic adherence is a problem of great impact worldwide, predominating mainly in patients with chronic diseases, in which long term adherence is little more than 50%, and even lower in developing countries. As a consequence, there are higher rates of hospitalization, increased health costs and therapeutic failures, among others. According to the World Health Organization (WHO), there are five factors involved in adherence: socioeconomic, treatment-related, patient-related, disease-related and health equipment-related. Although several plans have been described to improve adherence, with the evidence available so far, a specific strategies that is effective and useful in all cases can&#8217;t be recommended at this time.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Adherencia terapéutica]]></kwd>
<kwd lng="es"><![CDATA[cumplimiento de tratamiento]]></kwd>
<kwd lng="es"><![CDATA[tratamiento de enfermedades crónicas]]></kwd>
<kwd lng="en"><![CDATA[Therapeutic adherence]]></kwd>
<kwd lng="en"><![CDATA[adherence to treatment]]></kwd>
<kwd lng="en"><![CDATA[treatment of chronic diseases]]></kwd>
</kwd-group>
</article-meta>
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